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Interference of C604 on platelet aggregation pathways
Platelet adhesion and aggregation under flow | C604 alters the cell's major biophysical properties | Set the shear rate to model thrombosis
Cellix Technical Team
Feb 14, 20234 min read
93

VenaFlux : Accessories required to conduct a thrombosis assay using the VenaFlux setup
Quantify cell adhesion, rolling, migration, cell-cell adhesion, platelet aggregation, thrombi formation - all under shear flow.
Cellix Technical Team
Jan 30, 20232 min read
59

Adenosine Receptor Agonist HE-NECA Enhances Antithrombotic Activities of Cangrelor and Prasugrel
Test the effect of HE-NECA and cangrelor on thrombi formation | Platelet Activation and Thrombus Formation In Vitro |
Cellix Technical Team
Jan 23, 20233 min read
30


Cardiovascular: Platelets - Thrombosis Adhesion Assay
Novel microflow system | Low flow rates (5 pL min-1 to 10 μL min-1) and shear stress levels
Cellix Technical Team
Jan 16, 20235 min read
103

Cellix's VenaFlux Solutions mimic human blood vessels
Quantify cell adhesion, rolling, migration, cell-cell adhesion, platelet aggregation, thrombi ormation - all under shear flow.
Cellix Technical Team
Jan 9, 20233 min read
195


People are talking about our food
Thrombus formation under flow in vitro | Treatment with cucurbitacin | Pre-incubation of platelets with cucurbitacins
Cellix Technical Team
Jul 4, 20223 min read
190


Cellix's ExiGo Microfluidic syringe pump vs. conventional syringe pumps
5-phase stepper motor | Microfluidic syringe pump | Droplet Generation | Individualised programming | Thrombosis | Hydrodynamic flow focusin
Cellix Technical Team
Jun 10, 20222 min read
469

Selective Adenosine Receptor (AR) ligands modulate AR activity showing promise as clinical candidate
Inhibition of human blood platelets aggregation | Inhibition of human blood platelets aggregation | Formation of thrombus in flow conditions
Cellix Technical Team
May 31, 20224 min read
279

Bleeding diathesis in mice lacking JAK2 in platelets
The tyrosine kinase JAK2 protein is critical for the JAK/STAT cytokine signaling of hematopoietic cells. The somatic JAK2 V617F mutation...
Cellix Technical Team
May 6, 20223 min read
222

Inhibition of NADPH oxidase blocks NETosis & reduces thrombosis in heparin-induced thrombocytopenia
Microfluidic studies | Neutrophil-targeted ROS-inhibition assays | Thrombus formation in HIT requires neutrophil-derived ROS
Cellix Technical Team
Apr 8, 20224 min read
573

NETosis and thrombosis in vaccine-induced immune thrombotic thrombocytopenia
NETosis markers | Thrombosis induction | VITT antibodies induce thrombosis and thrombocytopenia in vitro
Cellix Technical Team
Mar 21, 20224 min read
379


Eucalyptol Inhibits Agonist-induced Platelet Function and Thrombus Formation in Mice
Thrombus Formation | Integrin αIIbβ3 Signaling | Granule Secretion in Platelets | Hemostasis
Cellix Technical Team
Feb 25, 20224 min read
133

Nanovesicles dissolve blood clots reducing side-effects
How does the nanovesicle work | Thrombus selectivity under physiological flow conditions | Targeted thrombolysis under flow conditions |
Cellix Technical Team
Jan 24, 20224 min read
306


Harnessing seaweed extract to treat ischemic stroke
On this World Thrombosis Day and in advance of World Stroke Day, taking place on 29th October, we’d like to shine a light on a paper recentl
Cellix Technical Team
Oct 11, 20214 min read
330


Blood clots in severely ill COVID-19 patients caused by abnormal antibody response
New study reveals blood clotting in critically ill COVID-19 may be caused by an excessive immune response rather than the virus itself.
Cellix Technical Team
Aug 23, 20214 min read
388

Assessing Plasma Infusion in cTTP patients with the VenaFlux platform
Congenital thrombotic thrombocytopenic purpura (cTTP) is a rare blood clotting disorder. Currently, there is no method to assess the...
Cellix Technical Team
May 18, 20215 min read
522


Shear Rate - what's it got to do with platelet adhesion?
As a thrombus (blood clot) grows in size, the blood has to be diverted over and around it. In order for blood flow to be maintained, the blo
Cellix Technical Team
Apr 20, 20214 min read
2,512


Standardised modelling of microclots in COVID-19 patients
Researchers set out to investigate if the spike protein interfered with blood flow, comparing naïve healthy PPP samples, with and without ad
Cellix Technical Team
Mar 15, 20214 min read
891

Trapped! Flow studies reveal Thrombosis target
The researchers of this study focused on how recruited platelets interact with neutrophils and whether this promotes the onset of Deep Vein
Cellix Technical Team
Oct 13, 20203 min read
260


Cellix Solutions mimic microvascular thrombosis accelerating COVID-19 research
For more than 15 years, Cellix has provided researchers with solutions for mimicking physiological conditions of human blood vessels and for
Dmitry Kashanin, CTO, Cellix
Jul 22, 20202 min read
426
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